Director or VP of Pre-clinical and Early Clinical Development

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POSITION TITLE:   Director or VP of Pre-clinical and Early Clinical Development

REPORTS TO:   President/CEO

POSITION TYPE:   Full time

SALARY RANGE:   Competitive, including equity

 

RESPONSIBILITIES:

Innovative and dynamic Biopharma with secured funding and exciting pre-clinical pipeline is seeking to bring a Director or VP level Development Head. The focus will be on oncology, immunology, and vascular health. The ideal candidate will help with translational research and development through to early phase clinical.

  • Identify, prioritize and mature early product opportunities
  • Oversee pre-clinical development activities including pharmacology, toxicology and pharmacokinetics
  • Guide early clinical development activities
  • Build Key Opinion Leaders relationships
  • Lead FDA preclinical and clinical interactions
  • Science portion of business plans including literature reviews

 

MINIMUM REQUIREMENTS:

  • MD or PhD training with 8+ years industry experience

 

Must have unrestricted work authorization to work in the United States.

To learn more, please contact Jobs@pharmain.com with subject: Head of Development, including any relevant and related support introduction details and your latest CV for full confidential consideration.

Senior Analytical Development Scientist—Analytical and Formulations Manager

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POSITION TITLE:   Senior Analytical Development Scientist—Analytical and Formulations Manager

REPORTS TO:   Director of CMC and QA

POSITION TYPE:   Full time

SALARY RANGE:   Negotiable based upon experience

 

RESPONSIBILITIES:

We are seeking a highly motivated Senior Analytical Development Scientist to perform methods development, qualification and tech transfer of assays for the analysis of nanopolymer containing formulations. The successful candidate will manage the analytical team within the CMC group.

 

REQUIREMENTS:

  • Minimum Master’s degree in biochemistry, chemistry, biotechnology or related field with 5+ yrs. relevant experience in the biotech/pharmaceutical industry; Ph.D. preferred
  • Hands-on experience in analytical methods development through validation of release assays supporting drug substance and drug product testing.
  • Experience contracting/managing CROs for product release testing from tech transfer to validation. • Authoring/reviewing reports and IND filings. Strong documentation and communication skills are very important.
  • Ability to build and manage small teams to complete projects with aggressive timelines.
  • Extensive experience with, colorimetric assay, chromatography (size exclusion, ion exchange and reversed-phase), fluorescence assays for the analysis of polymer protein and peptide containing samples/formulations using analytical instrumentation such as UPLC/HPLC, LC-MS, plate readers, light scattering and capillary electrophoresis) is required.
  • Experience with chemical and physical characterization of polymers. • Proactive, excellent timeline-focused problem-solving skills on multiple tasks oriented towards an overall goal, detail oriented, ability to handle multiple tasks simultaneously, to plan and prioritize tasks to meet timeline and overall goal and work efficiently.
  • A working knowledge of statistics is a must.
  • Must have unrestricted work authorization to work in the United States.

 

HOW TO APPLY:

Please email your resume to jobs@pharmain.com and include Senior Analytical Development Scientist in the subject line.

 

Research Associate/Research Scientist – Analytical Chemistry and Formulation

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POSITION TITLE:  Research Associate/Research Scientist—Analytical Chemistry and Formulation

REPORTS TO:   TBD

POSITION TYPE:   Full time

SALARY RANGE:   Negotiable based upon experience

 

RESPONSIBILITIES:

We  are  seeking  a  highly  motivated  Analytical  Development  Scientist  to  perform  methods development, qualification and tech transfer of assays for the analysis of nanopolymer containing formulations. The successful candidate will join CMC team.

 

REQUIREMENTS:

  • Minimum Master’s degree in biochemistry, chemistry, biotechnology or related field with 5+ yrs relevant experience in the biotech/pharmaceutical industry; Ph.D. preferred
  • Hands-­‐on  experience  in  analytical  and  bio-­‐analytical  chemistry  such  as  ELISA,  colorimetric assay, chromatography (size exclusion, ion exchange and reversed-­‐phase), fluorescence assay and enzyme assay. Bench experience in formulation and the use of analytical instrumentation (e.g. HPLC, LC-­‐MS, microscope, plate readers).
  • Experience  developing  chromatographic  separation  methods  for  polymer,  protein  and peptide containing samples.
  • Experience with chemical and physical characterization of polymers.
  • Proactive,  excellent  timeline-­‐focused  problem-­‐solving  skills  on  multiple  tasks    oriented towards an overall goal.
  • Detail oriented, able to plan and prioritize tasks, with strong time-­‐management skills.
  • Experience with pharmaceutical QC testing, assay qualification/validation and tech transfer
  • Understanding of animal experiments is a plus.
  • Excellent  ability  to  keep  lab  notebook  updated  daily  and  present  data  regularly  is  a  must. Strong documentation and communication skills are very important.
  • Computer skills including Word, PowerPoint, Excel or other graphing programs is expected.
  • A working knowledge of statistics is a must.
  • Must have unrestricted work authorization to work in the United States.

 

HOW TO APPLY:

Please email your resume to jobs@pharmain.com and include Scientist –  Analytical Chemistry in the subject line.

 

Peptide Chemist

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POSITION TITLE: Peptide Chemist

REPORTS TO: VP, Technology and Intellectual Property

POSITION TYPE: Full time

SALARY RANGE: Negotiable based upon experience

 

RESPONSIBILITIES:

We are seeking a highly motivated Peptide Chemist to:

  • Participate in peptide design/discovery and data-driven (structure activity relationship based) lead optimization.
  • Prepare (using automated solid-phase peptide synthesizer), purify, and characterize peptides
  • Maintain the team’s peptide synthesizers
  • Use and maintain HPLCs, LC/MS, and other instruments for peptide characterization and purification workflow
  • Development, submission, and maintenance QC data on files as well as on internal database
  • Planning, execution, and documentation of work under the guidance of the supervisor
  • Independently work on projects, solve problems, and meet project timelines
  • Application and/or Development of new linker chemistries, if needed

 

REQUIREMENTS:

  • Knowledge of organic chemistry and peptide synthesis strategies
  • Bachelor’s degree or higher (PhD. Preferred) with minimum of 3 years of industrial experience in the field of peptide synthesis
  • A creative and independent team member who thrives on benchwork
  • Ability to understand deadlines and commitments
  • Experience in using automated peptide synthesizer and knowledge of various synthesizer models and their maintenance is a must
  • Experience in running and maintaining LC-MS
  • Hands on experience in the HPLC analysis and purification (quantity from mgs to grams)
  • Experience in manufacturing, scale-up and tech transfer.
  • Proven analytical and problem-solving skills
  • Must be able to work on projects of a multidisciplinary nature
  • Must be a self-starter, highly motivated, organized, and able to work in a team environment
  • Communicate clearly in written and verbal forms as well as understand written and verbal communication
  • Strong work ethic and willingness and ambition to learn and take on responsibilities
  • Must have unrestricted work authorization to work in the United States.

 

HOW TO APPLY:

Please email your resume to jobs@pharmain.com and include Peptide Chemist in the subject line.

 

Research Associate – Biology

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POSITION TITLE: Research Associate – Biology

REPORTS TO: TBD

POSITION TYPE: Full time

SALARY RANGE: Negotiable based upon experience

 

RESPONSIBILITIES:

We are seeking a highly motivated Research to support our growing Biology team.  The successful candidate will enjoy working in a fast-paced environment, and have hands-on experience with laboratory maintenance, cell culture, ELISA, and laboratory rodent handling.

 

REQUIREMENTS:

  • B.S. in Biology or a related field with 1+ yr. relevant experience. Industry experience is preferred.
  • Experience working with laboratory rodents.
  • Familiarity with ELISA; experience with ELISA automation is a plus.
  • Mammalian cell culture experience.
  • Ability to manage time in a fast-paced environment.
  • Ability to keep accurate laboratory notebooks and other records.
  • Must have unrestricted work authorization to work in the United States.
  • Be available to work on weekends.

Please email your resume to jobs@pharmain.com and include: Research Associate – Biology in the subject line. For more information, please visit our website: www.pharmain.com