Scientific Publications

Antiretroviral Hydrophobic Core Graft-Copolymer Nanoparticles: The Effectiveness against Mutant HIV-1 Strains and in Vivo Distribution after Topical Application
Anita Leporati, Suresh Gupta, Elijah Bolotin, Gerardo Castillo, Joshua Alfaro, Marina B. Gottikh, Alexei A. Bogdanov Jr. Received 07 December 2018 / Accepted / 05 March 2019 / Published Online 27 March 2019

Omeprazole and PGC-Formulated Heparin Binding Epidermal Growth Factor Normalizes Fasting Blood Glucose and Supresses Insulitis in Multiple Low Dose Streptozotocin Diabetes Model
Gerardo M. Castillo & Akiko Nishimoto-Ashfield & Aryamitra A. Banerjee & Jennifer A. Landolfi & Alexander V. Lyubimov & Elijah M. Bolotin.   Received: 27 March 2013 / Accepted: 4 June 2013 / Published online: 21 June 2013

Hydrophobic-core PEGylated graft copolymer-stabilized nanoparticles composed of insoluble non-nucleoside reverse transcriptase inhibitors exhibit strong anti-HIV activity
Anita Leporatia, Mikhail S. Novikovb, Vladimir T. Valuev-Ellistonc, Sergey P. Korolevd, Anastasia L. Khandazhinskayac, Sergey N. Kochetkovc, Suresh Guptaa, Julian Godinga, Elijah Bolotine, Marina B. Gottikhd, Alexei A. Bogdanov Jr.  Received: 1 April 2016 / Accepted: 11 July 2016

Protected Graft Co-polymer (PGC) Basal Formulation of Insulin as Potentially Safer Alternative to Lantus® (Insulin-Glargine): A Streptozotocin-Induced, Diabetic Sprague Dawley Rats Study
Sandra Reichstetter, Gerardo M. Castillo,  ManShun Lai,  Akiko Nishimoto-Ashfield,  Aryamitra Banerjee,  Alexei Bogdanov, Alexander V. Lyubimov, Elijah M. Bolotin.  Received: 28 July 2011 / Accepted: 5 December 2011

Extending Residence Time and Stability of Peptides by Protected Graft Copolymer (PGC) Excipient: GLP-I Example
Gerardo M. Castillo,  Sandra Reichstetter, Elijah M. Bolotin. Received: 6 May 2011 / Accepted: 14 July 2011 / Published online: 4 August 2011

Protected Graft Copolymer Excipient Leads to a Higher Acute Maximum Tolerated Dose and Extends Residence Time of Vasoactive Intestinal Peptide Significantly Better Than Sterically Stabilized Micelles
Sandra Reichstetter,  Gerardo M. Castillo, Israel Rubinstein, Akiko Nishimoto-Ashfield, ManShun Lai, Cynthia C. Jones, Aryamitra Banjeree, Alex Lyubimov, Duane C. Bloedow, Alexei Bogdanov Jr., Elijah M. Bolotin. Received: 17 May 2012 / Accepted: 8 October 2012 / Published online: 7 December 2012

Protected Graft Copolymer (PGC) in Imaging and Therapy: A Platform for the Delivery of Covalently and Non-Covalently Bound Drugs
 Alexei A. Bogdanov Jr, Mary Mazzanti, Gerardo Castillo, Elijah Bolotin. Received: 2012.01.10 / Accepted: 2012.02.17 / Published: 2012.06.04

Protected Graft Copolymer-formulated Fibroblast Growth Factors Mitigate the Lethality of Partial Body Irradiation Injury
Gerardo M. Castillo*, Akiko Nishimoto-Ashfield, Cynthia C. Jones, Kasim K. Kabirov, Alexander Zakharov, Alexander V. Lyubimov. Received: August 11, 2016  / Accepted: January 23, 2017  / Published: February 16, 2017